Timing of surgical antimicrobial prophylaxis

Evaluating the optimal timing of surgical antimicrobial prophylaxis: study protocol for a randomized controlled trial

BACKGROUND Surgical site infections are the most common hospital-acquired infections among surgical patients. The administration of surgical antimicrobial prophylaxis reduces the risk of surgical site infections . The optimal timing of this procedure is still a matter of debate. While most studies suggest that it should be given as close to the incision time as possible, others conclude that th...

Precise timing might not be crucial: when to administer surgical antimicrobial prophylaxis.

The prevention of postoperative surgical site infection (SSI) involves measures before surgery; one such measure is surgical antimicrobial prophylaxis (SAP). Optimum practice for SAP includes choosing the right drugs, administration of these at the right time, and discontinuing them within 24 h after surgery. The recent WHO recommendations on preoperative measures for SSI prevention based on a ...

Timing of surgical antibiotic prophylaxis administration: Complexities of analysis

BACKGROUND The timing of prophylactic antibiotic administration is a patient safety outcome that is recurrently tracked and reported. The interpretation of these data has important implications for patient safety practices. However, diverse data collection methods and approaches to analysis impede knowledge building in this field. This paper makes explicit several challenges to quantifying the ...

Developing Surgical Antimicrobial Prophylaxis Interventions Using Theoretical Domains Framework

Optimal Timing of Surgical Antimicrobial Prophylaxis with Cefuroxim: Challenging the WHO Guidelines with 121,000 Prospectively Followed Patients